FREE Shipping Available

drawer icon
profile-icon

Sign In

cart-no-item

Hair Loss

Erectile Dysfunction

Weight Loss

Birth Control

Emergency Contraception

Diabetes Management

Migraine

Presbyopia

Insomnia

Specialty

treatment image

Hair Loss

Say goodbye to embarrassment and get back to feeling like you.

messages icon

Certified prescriptions

messages icon

Fast, online telehealth visits

messages icon

Over 1 million patients served

WEIGHT LOSS

A bit lighter feels a whole lot better

Weight loss has never been easy. Closing in on your ideal body takes a lot less effort with the right treatment. UpScript isn’t focused on what others think is perfect, we’re focused on a happier you.

CHOOSE TREATMENT
panel image

Treatment for Weight Loss

CONTRAVE®

Lose weight and keep it off with the #1 prescribed weight-loss pill. Contrave helps ward off cravings and pairs perfectly with a healthy diet and regular exercise to keep off the pounds. Replace hunger with confidence and reach real, achievable goals.

product information image

Men and women aged 18+

product information image

120 tablets (1-month supply)

product information image

Online consultation

$99.00 /120 tablets

LEARN MORE
feature-information
Know your weight loss goal

You’ve tried losing weight naturally but it’s just not cutting it. You aspire to feel better every day and are ready to start a treatment to get you there. We’ll help curb hunger and control your cravings.

feature-information
Book an online visit

Talk to one of our many professionals ready to tell you what’s what about weight loss. They’ll learn just enough about your lifestyle to know which treatment is the right fit.

feature-information
Order and get started

Skip the pharmacy trip and get your prescription delivered directly. Start your treatment. Need a refill? No problem, just come on back and re-order with ease.

feature-information

NO SWEAT

Weight loss treatments take little effort to try

Dieting and exercise both require time and effort and may not be entirely effective if there are other, underlying causes to your weight gain. Our providers can help pinpoint what is preventing healthy loss and get you on track to feeling better than ever.

feature-information

FOR WHOM?

You don’t feel good about your weight & have tried to lose it

Weight loss is a very personal journey but you don’t have to traverse alone. Weight loss treatments are available that help combat hunger receptors in the brain and are best paired with improved diet and exercise.

feature-information

EXPECTATIONS

What have you got to lose?

It can be frustrating trying to lose weight, but it’s not impossible. The most important consideration is that there’s no magic pill—it’s a combination effort. Reaching your goal won’t happen instantly. With an improved lifestyle and a little time, you’ll notice progress toward your goals and feel more confident every day.

Still curious? Here’s what others are asking

What is CONTRAVE?

expand icon

CONTRAVE® (naltrexone HCI/bupropion HCl) is a prescription weight-loss medicine that may help adults with obesity (BMI greater than or equal to 30 kg/m2), or who are overweight (BMI greater than or equal to 27 kg/m2) with at least one weight-related medical condition, lose weight and keep the weight off. CONTRAVE should be used along with diet and exercise.

What are the main ingredients?

expand icon

CONTRAVE contains two well-known FDA-approved drugs, naltrexone and bupropion that, individually, have been on the market for over 30 years. Naltrexone is an anti-addiction medication approved to treat alcohol and opioid dependence. Bupropion is an antidepressant approved to treat depression and seasonal affective disorder and is an aid to smoking cessation treatment. (These individual drugs are not approved for weight loss and CONTRAVE is not indicated for the treatment of depression, smoking cessation, or alcohol or opioid dependence.)

How does weight loss medication work?

expand icon

The exact neurochemical effects of CONTRAVE leading to weight loss are not fully understood. CONTRAVE is believed to work on two areas of the brain—the hypothalamus (your hunger center) to help reduce hunger and the mesolimbic reward system to help control cravings—that can get in the way of weight loss. Across three one-year studies, nearly half of patients taking CONTRAVE along with diet and exercise lost 5% or more of their body weight versus 23% of patients with diet and exercise alone (placebo).

Does treatment work for everyone?

expand icon

CONTRAVE is approved for use in adults with a body mass index (BMI) of 30 or greater (obese) or 27 or greater (overweight) who have at least one weight-related condition, such as high blood pressure, type 2 diabetes, or high cholesterol. It is to be used along with a reduced-calorie diet and increased physical activity.

 

CONTRAVE is not for everyone. Do not take CONTRAVE if you:

  • Have a seizure disorder
  • Are pregnant or trying to get pregnant
  • Have an eating disorder such as anorexia or bulimia
  • Are under the age of 18
  • Have uncontrolled hypertension
  • Use other medicines that contain bupropion such as Wellbutrin and Aplenzin
  • Are dependent on opioid medicines or use medicines to help stop taking opioids, such as methadone or buprenorphine or are in opiate withdrawal
  • Drink a lot of alcohol and abruptly stop drinking
  • Use medicines called sedatives like benzodiazepines, or anti-seizure medicines, and you stop using them suddenly
  • Are allergic to any of the ingredients in CONTRAVE, such as naltrexone HCI and bupropion HCI
  • Are taking medicines called monoamine oxidase inhibitors (MAOIs)

 

To learn more, see the Medication Guide.

What should I know when starting Contrave?

expand icon

CONTRAVE should be taken by mouth in the morning and in the evening and should not be taken with high-fat meals.

 

CONTRAVE dosing should be increased slowly according to the following schedule:

Standard Dosage for Patients Taking Contrave
Tablets not shown to size.

 

It’s important to take CONTRAVE exactly as your doctor prescribes it. Keep in mind that some people, like those with renal or hepatic impairment, or those taking certain other medications, may need to follow a different dosing schedule. A total daily dosage of four CONTRAVE tablets (i.e., two tablets taken twice per day) should be reached at the start of week four.

 

To learn more about dosing, see the Medication Guide

 

Common Side Effects & Tips for Managing Them
The most common side effects reported with CONTRAVE include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea. For most people, these symptoms went away within the first four weeks of taking CONTRAVE. If symptoms do not improve, please consult with your healthcare provider.

 

In general, it is recommended you drink plenty of water when taking CONTRAVE. If you experience nausea, you may also want to eat a small amount of dry toast with CONTRAVE. If symptoms do not improve, please consult with your doctor who may also recommend an over-the-counter anti-nausea medication for you.

Need Help?

Speaking with our expert telehealth team is fast and easy. Email, call us, or start a live chat below.

service@UpScript.com

Please refer press inquiries to
press@upscripthealth.com

(844) 723-3103

Start Live Chat

Treatments

treatment

Hair Loss

Erectile Dysfunction

Weight Loss

Birth Control

Emergency Contraception

Diabetes Management

Migraine

Presbyopia

Insomnia

Specialty