FREE Shipping Available

profile-icon

Sign In

cart-no-item

Hair Loss

Erectile Dysfunction

Weight Loss

Birth Control

Emergency Contraception

Diabetes Management

Migraine

Presbyopia

Insomnia

Specialty

treatment image

Hair Loss

Say goodbye to embarrassment and get back to feeling like you.

messages icon

Certified prescriptions

messages icon

Fast, online telehealth visits

messages icon

Over 1 million patients served

product image

ONZETRA® Xsail®

$45.00/Visit

promotion-icon

Prescriber visit fee for new prescriptions

Migraine help is just a few clicks away. Talk to an online healthcare provider to find out if a prescription is right for you. ONZETRA® can provide fast and effective relief. Pay as little as $0 for ONZETRA®. Terms and Conditions apply.
product feature icon

Patients ages 18+

product feature icon

A non-oral treatment

product feature icon

Online Consultation

$45.00/Visit

promotion-icon

Prescriber visit fee for new prescriptions

Important information

drawer icon

IMPORTANT SAFETY INFORMATION

For additional Important Safety Information about ONZETRA Xsail, please see the full Prescribing Information, including Patient Information and Instructions for Use.

Serious Side Effects
Warnings
Precautions
Additional Side Effects

Serious Side Effects

ONZETRA Xsail may cause serious side effects, including:

  • Heart attack and other heart problems, which may lead to death. Stop using ONZETRA Xsail and get emergency medical help right away if you have any symptoms of a heart attack like shortness of breath or tightness, pain, pressure, or heaviness in your chest, throat, neck, or jaw that is severe or does not go away
  • Changes in color or sensation in your fingers and toes (Raynaud’s syndrome)
  • Stomach and intestinal problems (gastrointestinal and colonic ischemic events)
  • Problems with blood circulation to your legs and feet (peripheral vascular ischemia)
  • Serious allergic reactions (symptoms include hives; tongue, mouth, lip, or throat swelling; problems breathing)
  • Medication overuse headaches. Some people who use ONZETRA Xsail too many times may have worse headaches. If your headaches get worse your doctor may decide to stop your treatment with ONZETRA Xsail
  • Serotonin syndrome, a rare but serious problem that can happen in people using ONZETRA Xsail, especially if ONZETRA Xsail is used with antidepressant medicines called SSRIs, SNRIs, or TCAs.
  • Call your doctor right away if you have any of the following symptoms of serotonin syndrome: mental changes such as seeing things that are not there (hallucinations), agitation, or coma; fast heartbeat; changes in blood pressure; high body temperature; tight muscles; trouble walking; or nausea, vomiting, or diarrhea
  • Seizures. Seizures have happened in people taking sumatriptan who have never had seizures before

ONZETRA® Xsail®

can provide fast, effective relief that can last

A different way to treat migraine

For many patients suffering from acute migraines an oral medication, like a pill may not always be the best option in the moment. That’s why ONZETRA® Xsail®, a non-oral treatment maybe an option for you. The unique Xsail® device uses the power of your own breath to deliver medicine directly to the back of your nose–it’s sumatriptan taken differently! The back of your nose is full of absorbent tissue and blood vessels, so the powder medication is absorbed quickly.

You are not alone

According to the American Migraine Foundation, migraines impacting more than 39 million people in the U.S. alone. Migraine is a neurological disease. During a migraine attack, your nerves release signals that cause the blood vessels in your brain to expand. This may result in an increased sensitivity to light, sound or smells during a headache. The World Health Organization named migraine as one of the 10 most disabling illnesses. Learn more about migraines at https://www.americanmigrainefoundation.org/

Patients seek out more tools in their migraine tool box

In a recent survey conducted by the National Headache Foundation (NHF) a total of 3 in 4 individuals told researchers their medications didn’t work quickly enough on migraines that come on suddenly or arise upon awaking. 54% told researchers that their current oral migraine medication didn’t help with every attack and 51% said their were dissatisfied overall with their migraine medications. Don’t let a migraine slow you down, adding an additional treatment to your migraine tool box may provide extra support when you need it most.

Need Help?

Speaking with our expert telehealth team is fast and easy. Email, call us, or start a live chat below.

service@UpScript.com

Please refer press inquiries to
press@upscripthealth.com

(844) 723-3103

Start Live Chat

Treatments

Hair Loss

Erectile Dysfunction

Weight Loss

Birth Control

Emergency Contraception

Diabetes Management

Migraine

Presbyopia

Insomnia

Specialty

Experience

How It Works

FAQs

About Us

Our Story

Careers

Support